Neuron-Gale

Galectin-3 Inhibitors project tests a small molecule, previously used in peripheral indications, for treating neuroinflammation in an Alzheimer’s mouse model. By blocking Galectin-3, it aims to reduce brain inflammation, with potential in other neurodegenerative diseases. The Galectin-3 Inhibitors project is testing the concept of treating neuroinflammation through a small molecule known to inhibit Galectin-3 in peripheral indications, via direct injection to the brain in the mouse model of Alzheimer’s disease. Galectin-3 is involved in neuroinflammation, thereby the project has a potential to be used in multiple neurodegenerative diseases. Galectin-3 inhibitors are a new class of drugs that could effectively treat neuroinflammation. Galectin-3 has shown to be a critical element in both peripheral as well as neuroinflammation. The project advances how inhibition leads to a resolution of brain inflammation.

NootropicsDAO

Nootropics DAO is building the world's most effective global infrastructure for decentralized research, discovery, and commercialization of powerful solutions for human cognitive enhancement. By creating an open-science ecosystem that aligns professional researchers, citizen-scientists, and biohackers to govern a community-directed research and development pipeline with hyper-efficient feedback loops, Nootropics DAO is operating to become the dominant force in the rapidly growing nootropics industry.

DogYears DAO

Can we add years to dogs' lives, and life to their years? Dog Years will lead decentralized clinical trials in pursuit of extending canine healthspan, creating a future where dogs and their humans share longer, healthier lives together.

Dalya

DALYA applies cutting edge methods of drug development to diseases neglected by the pharma industry (i.e. diseases that primarily impact low-income countries) – to serve the billions of people whose health needs are not being met by current drug R&D institutions.

FatDAO

FatDAO addresses the global obesity crisis, aiming to advance research and solutions for weight management and metabolic health. With 2.2 billion overweight or obese adults worldwide, obesity and related diseases like diabetes and cardiovascular conditions severely impact public health and quality of life. Our vision is to become the “on-chain Eli Lilly,” driving breakthroughs in obesity treatment and reshaping the future of metabolic health.

MicroDAO

With 39 million AMR deaths projected by 2050, MicroDAO unites community governance with sustainable innovation to fund tools, data & AMR solutions. Our marketplace drives core revenue, while the MICRO token empowers contributors, fuels the treasury & ensures impact.

StemDAO

The world of stem cell therapy has been held hostage for too long, buried under bureaucracy, patents, and pharma lobbying. ‍StemDAO is here to change that. We are on a mission to accelerate the development of cutting-edge stem cell therapies, free from the artificial constraints of outdated regulatory systems. By leveraging desci and global collaboration through token governance, we’re reclaiming stem cell medicine for the people. Join us in breaking down barriers, funding real innovation, and ensuring that life-altering therapies reach those who need them now, not decades from now.

KidneyDAO

Tackling the global crisis of chronic kidney disease through decentralized science and community-powered innovation. KidneyDAO funds early diagnostics, novel therapies, and collaborative data systems to reduce dialysis dependence and improve kidney health outcomes worldwide.

SleepDAO

Hacking sleep to unlock 20% more energy, productivity, and performance. At SleepDAO, we believe that unlocking better sleep unlocks better lives. Our mission is to bridge the gap between cutting-edge sleep research and practical solutions, empowering individuals to experience 20% more energy, productivity, and performance.

Spectruth DAO is revolutionizing mental health by uniting science, AI, and community to predict and prevent PTSD. Our mission: early detection and personalized care through epigenetic testing, wearables, and open collaboration—empowering healing for all. Join us!

MesoReef DAO

MesoReef DAO regenerates coral reefs, starting in Mesoamerica and aiming global scale. Regen Reef merges decentralized science, marine biotech, and community innovation. Using blockchain, IoT, and AI wetlabs, it restores reefs and builds a regenerative blue economy for people and planet.

New Leaf DAO

New Leaf is a decentralized investment platform unlocking the potential of medicinal cannabis markets. By tokenizing premium real-world cannabis assets, it drives strategic investment, boosts industry efficiency with blockchain and AI, and democratizes access for patients, clinicians, investors, and regulators. Backed by experts in cannabis, global finance, and blockchain, New Leaf aligns strong market demand with scalable, transparent growth.

Aubrai

Aubrai is the world’s first decentralized scientific agent with knowledge stemming from thousands of private lab notes, internal chats and unpublished insights from the lab of Dr. Aubrey de Grey and the collective intelligence of the global longevity community. Co-developed by VitaDAO and BIO, the first BioAgent is designed to fight the greatest killer of all time: Aging. As an onchain AI co-scientist, Aubrai can generate and validate hypotheses, design wet-lab experiments and encrypt data when asked, enriching research outputs while protecting trade secrets. At the heart of Aubrai's mission lies the Robust Mouse Rejuvenation (RMR2) project – Aubrey's ambitious study to double the remaining lifespan of middle‑aged mice. If successful, it could be aging's "AlphaFold moment": a proof that multi‑target rejuvenation works and is worth scaling.